Karine Jean-Pierre (born August 13, 1974) is an American political advisor and spokesperson who served as the 35th White House press secretary from 2022 to 2025, and as a senior advisor to President Joe Biden from 2024 to 2025. She is the first Black person and the first openly LGBTQ person to serve in the position of White House press secretary. Previously, she served as deputy press secretary to her predecessor, Jen Psaki, from 2021 to 2022, and as the chief of staff for U.S. vice presidential candidate Kamala Harris during the 2020 presidential campaign.

Prior to her work with Harris during the 2020 election and with the Biden–Harris administration, Jean-Pierre was the senior advisor and national spokeswoman for the progressive advocacy group MoveOn.org. She was also previously a political analyst for NBC News and MSNBC and a lecturer in international and public affairs at Columbia University.

In June 2025, Jean-Pierre announced that she had left the Democratic Party and was now an independent.