A woman calls the police after she recognizes Kimble's picture on a TV quiz show and in the ensuing manhunt, Kimble hides out in a home for the blind. Kimble becomes acquainted with some of the residents, including the attractive Claire Whittaker whom he assists, as well as Pete Haskell whom Kimble discovers is not really blind and was actually temporarily blinding in a school bus accident months earlier which Pete blames himself since he was driving drunk at the time. But one of the residents is a certain Dan Brady, a veteran lawman whom was blinded in the line of duty and has now been put out to pasture. Brady remains bitter for having lost his position as the town's sheriff to the younger, more educated, but less experienced, Barney Vilattic. When Brady suspects Kimble's true identity, he sees an opportunity to capture the fugitive to reclaim his former job.

While working as a veterinarian assistant in a rural town in Utah, Kimble becomes aquainted with Ruth Simmons, an unwed teenage mother whom has a sickly infant. But her father, Joshua, is a Christian Scientist whose religion prohibits the use of medicine for any ailment. Kimble brings over antibiotics, but Joshua destroys the drugs. After determing that the baby is anemic, Kimble secretly arranges for a blood transfusion. Meanwhile, after stumbling upon Kimble's true idenity, a would-be deputy, named Pete, searches for the fugivtive with the aid of his two bloodhound dogs.