Life hangs in the balance for Josh and Finlay when their ambulance crashes dramatically into a railway bridge. And the arrival of Duffy's baby is imminent.

An angst-ridden Josh is in even hotter water when he comes face-to-face with the sister of the boy he killed, and Colette's teenage daughter announces she's pregnant.

New doctor Lara Stone is thrown straight in the deep end. Charlie meets the new chief executive in unexpected circumstances - a supper club for singles!

Comfort and new paramedic Nikki deal with a series of harrowing incidents - a patient with paranoid schizophrenia, a horrific building site accident and a dying priest.

Lara ignores warnings to observe hospital protocol when the life of a pregnant woman and her unborn child hang in the balance.

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Has Chloe bitten off more than she can chew? Dillon is forced to expose details of Patrick's relationship with Rachel when Lara reveals she is keen on Patrick.

A group of friends cause havoc at their annual firework display. Jack's practical joke on Charlie backfires.

Comfort is stabbed while breaking up a fight, and a student forces Josh to consider the implications of his resignation.

Duffy becomes involved with a bereaved father and son on her first day back. Meanwhile, Spencer finds himself having to play referee between a warring couple.

Max and Amanda face an emotional dilemma as Ben is brought in to Accident and Emergency. Patrick has to make a difficult decision regarding Max's rule bending.

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Comfort and Nikki have to pick up the pieces when a load of football fans make an unexpected entrance into a rival pub. Patrick faces the wrath of a vengeful husband.

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Chloe finds herself out of her depth when she treats a convicted killer with a fear of anaesthetic.

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The consequences of the train crash begin to hit home. Comfort struggles to come to terms with what has happened. And Jim warns Nikki not to get involved with Paul.

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Comfort is disgusted when female members of staff strike raunchy poses for a charity calendar, and Tally works out that Harry has been self-prescribing.

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Harry's attempt to kiss Lara at the calendar launch backfires, Comfort is led astray by a friend out for a good time, and Roxy confesses to being a surrogate mother.

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Jim whisks Nikki away for a cosy weekend at his remote country house, Bex drowns her sorrows in wine and cigarettes, and Charlie's son finally responds to treatment.

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I Got It Bad and That Ain't Good: Luke feels responsible for a man's death at an Army barracks, while the love triangle between Baz, Dan and Charlie reaches a dramatic climax.

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Lara dives underwater to save Simon, Fin sends Comfort home drunk and Jim struggles to keep order when the hospital is besieged by patients.

Valentine's Day proves traumatic for the staff at Holby A&E, as Nikki tries to decide what to do about her pregnancy, and Comfort and Fin struggle to handle their break-up.

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The attraction between Simon and Lara proves too strong to resist, Roxy tries to stop Nikki going ahead with the termination and Comfort misses her counselling session.

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Roxy goes into premature labour, causing Nikki to put her grievances aside to help deliver the baby in the back of her car.

Roxy gives her baby away, but the new parents are far from happy with the bundle of joy. Comfort prepares for her last day, and Tally manipulates her father.

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Tally hits rock bottom after Harry suspends her and Simon tells her she was his biggest mistake, while Roxy faces heartbreak when the surrogate parents want the baby.

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Abs is attacked by a man who blames him for the death of his child, while Harry realises he has been neglecting Tally and suggests they take a holiday together.

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Harry's return to work prompts Charlie to draft his resignation letter, Fin and Comfort enjoy a romantic picnic, while Nikki and Lara are taken hostage.

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Nikki's slow recovery from the fall is set back by devastating news, Luke reluctantly attends the inquest, and Kate insists Greg's death was his fault.

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New paramedic Nina makes a bad impression, Josh's date with Caroline turns out to be an unmitigated disaster, and Lara is forced to take desperate measures.

Nina annoys the rest of her team by playing the heroine. Simon is summoned to see Harry, Caroline pulls away from Josh, and Bex is on cloud nine.

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Tess treats a woman who has been severely beaten, and attempts to find out how she came by her injuries, while Simon and Lara celebrate their stag and hen nights.

Lara's big day is put in jeopardy when Abs makes a shocking discovery and the plane taking Simon to the wedding crashes and explodes.