In order to prove to Krendler and the VICAP team that she is fit for duty, Clarice must find the psychological key that will unlock a confession from the suspect in the three river murders.

Clarice and Ardelia team up to investigate a deeply twisted cold case after the body of a missing teenager is found entombed in concrete. Also, Clarice wrestles with the knowledge that Krendler may know the man who attacked her while she was held captive.

Catherine Martin escapes to Carneys Point, N.J., to confront Buffalo Bill’s mother, Lila Gumb. When Ruth recruits Krendler and ViCAP to track her down, Clarice volunteers to be the one to find Catherine before she commits a vile act and becomes a monster herself. Also, Julia continues to assist the ViCAP team’s investigation despite the huge personal risk.