Wayne works with the joint Mexican-American "Fusion Center” to track the sicarios responsible for the recent bloodshed. Isa ignores orders to stay in the embassy and instead pursues a lead to the Guerrero Cartel. And Lalo puts his career at risk, battling the Mexican President for control of the narco investigations.

Wayne's off-the-books operations finally catch up to him as Isa's fiancé pursues a lead that could put both Wayne and Isa in jail. Isa has to create a fake asset to cover up for Wayne’s misbehavior. Meanwhile, Bautista threatens Wayne’s life, but mysteriously, and ominously, lets him live. Veronica starts to realize the truth about her marriage. And Lalo gets his hands dirtier than ever before.

In the aftermath of the previous episode, Wayne, Isa, Veronica and Lalo all come to realizations about their lives and relationships. By the season’s end, the previous alliances have been destroyed and new ones are being built. And our main characters have to prepare for war, with new battle lines drawn.