West tries to protect Prof. Nielsen, a demolitions expert. But he fails: Nielson is blown up by the evil Dr. Miguelito Loveless.

West is lured to a ghost town peopled with lifelike dummies as part of an elaborate trap set for him by his nemesis Dr. Loveless.

West helps a powerfully built girl carry her trunk, not knowing it contains his shrewd enemy---diminutive, giggling Dr. Loveless.

The evil, diminutive Dr. Loveless impoverishes an Indian tribe so that he can become their benefactor -- and their god.

Agents West and Gordon are guarding a museum containing the famous Herzberg jewels but someone still manages to steal the gems. Afterward, a famous painting of a Western scene is removed from the museum by its wealthy rancher-owner. Gordon becomes suspicious and notifies West who discovers that the rancher is partners with Miguelito Loveless, the evil inventor-doctor. His latest invention is a machine that moves real people in and out of paintings. Miguelito's plan is to transpose murderers into famous paintings, distribute the paintings to the rulers of the world, and have them all killed!

Dr. Loveless is back with another plan to take over the world. This time he is using mock-ups of the treasury, prisons and armories to train his men to be able to take over these resources upon his command. After gaining control, Loveless will be instituted as dictator. However, his plan to get rid of West and Gordon goes foul and soon the agents are in hot pursuit of the little villain.

The agents travel to Hayes City to identify the body of their archnemesis, Dr.Loveless. While there, they meet up with Miguelito's next of kin, Dr.Liebknicht, a Swiss neurologist. However, as they pursue the origin of a key found on the body, they find that Loveless is hardly dead and has plans to use his neurologist guise to give Jim a lobotomy!

Agent West is summoned by a note from agent Gordon to the local barbershop. While waiting for Gordon, West decides to have a shave and is promptly anesthetised by a hot towel from one of Dr. Loveless's assistants, working in disguise. When he wakes up, he finds himself in a carnival funhouse where he encounters dazed-looking Justice Alonzo Fairlie. Before he can get any information from the judge, he is attacked by a quartet of gunmen. He quickly dispatches his adversaries but Justice Fairlie disappears in the confusion, leaving behined a strange clue.