In the midst of a crisis, Don runs into an old friend.

For the Draper family, life has changed. The children must adapt to a new home, a new brother, and a new stepmother. Don seems to have everything a man could want. However, Megan, still employed at the agency, has difficulty interpreting Don's expectations for a sex kitten at home and a prim and proper employee at the office.

As Sterling Cooper Draper Pryce tries to build upon its current business, Peggy is given new responsibility. Don and Harry indulge a client. Betty contemplates her mortality after seeing a doctor.

Peggy has a tough time during a particularly formidable pitch. Don calls on a potential client. Roger and Jane have an experience with LSD.

Don is honored at a banquet for the American Cancer Society, but finds his professional reputation has been damaged. Sally lends a hand to a relative. Megan's parents come to visit from Canada.

While Don continues his affair with Sylvia, Pete's latest infidelity threatens his marriage. Meanwhile, Peggy's icy relationship with her new staff continues, but she also gets an unlikely tip on a potential new client.