Sky-high OxyContin sales are threatened by reports of abuse, prosecutors investigate a claim central to OxyContin marketing, and Finnix begins to question the safety of the drug.

Richard Sackler faces a catastrophic challenge to Purdue’s bottom line, Bridget takes her fight to the FDA, Finnix reassesses his life as Betsy struggles to kick her addiction, and Rick and Randy find a bombshell piece of evidence.

Richard Sackler and Purdue work the system to prevent their drug from being reigned in, Bridget has a breakthrough in her mission, Betsy has hit rock-bottom while Finnix explores new avenues, and Rick and Randy ready their criminal case.