Four years had passed since Sagan's called a truce with the D2s. Music was still taboo throughout the world, and melodies ceased to be heard. Somewhere in America, which was now a wasteland, a little boy who grew up not knowing what music is hears the melody from a piano. The one playing it is a young man with black hair named Takt. And then, a deformed creature known as a D2 and a girl named Destiny, who is armed with a sword, appear as though they were lured in by the melody.

It all began ten years ago. D2s attacking Boston, a blood-soaked concert hall: The incident known as the Boston Tragedy. The conductor who lost his life in that tragedy was none other than Kenji Asahina, Takt's father. After losing his father, the boy decides to devote himself to playing the piano and he lets his rage play through his melodies. The one who took care of him was a girl named Cosette, who looked just like Destiny.

Destiny is terribly cruel. But no matter how much misfortune the gods torment me with, I will face my destiny. Because of that, I fought, and I fought, and I fought some more... And then, I finally found my answer. There truly was joy beyond the pain. Now, it is time for the performance to begin. I shall now wring destiny's neck. "From a certain man's memoirs"