In an attempt to honor Lisa's last wishes, Nate finds himself at odds with her family. Meanwhile, David and Keith look for 'genuinely new' ways to start over; Federico seeks out a priest for absolution; Vanessa gets tired of Angelica; Brenda does 'the neighbor thing' with Joe; and Ruth sings the praises of her new husband George.

A group of prank-happy teenagers find their latest joke is no laughing matter. Meanwhile, the Fishers decide to hold a yard sale; David grooms Arthur for a new role; Nate gets intimately involved in Maya's afternoon playgroup; Claire attends an art party; Ruth and George receive some unwanted wedding gifts; Federico gets caught up in family responsibilities; Keith adjusts to the peculiarities of his new job; Joe isn't thrilled by Brenda's yearning for normalcy; and some important memories go up in smoke.