Eli Stone finds his life at a crossroads and soon learns that he suffering from an inoperable brain aneurysm that's causing his hallucinations. Struggling to cope with the news, Eli begins to have visions that he is a prophet and decides to use his new found abilites for good.

Eli has a revelation when a man appears on his TV set and asks for help. The man turns out to be one of Nathan's patients who just awoke from a coma after five years to find his wife has taken over his company and has a new husband. He asks Eli to sue in order to get his life back on track.