S.H.I.E.L.D. organizes a full scale hunt for Coulson. Meanwhile, Coulson uncovers vital information about the mystery of his death, but, with Centipede out for blood, this knowledge may come at the cost of one of the team!

As Robert Gonzales makes his move, Coulson must do whatever it takes to protect the future of S.H.I.E.L.D. Meanwhile Skye’s journey to control her powers takes a surprising turn when she meets the enigmatic Inhuman named Lincoln.

Daisy decides she will rescue Simmons, even if it means risking everything to do it.