When floating bodies turn up, Coulson and the agents of S.H.I.E.L.D. must hunt down an elusive killer. No one is safe - not even the team.

Agents Garrett and Triplett are back to help Coulson's Team track down S.H.I.E.L.D.'s nefarious enemy--The Clairvoyant. But will Deathlok destroy them all to protect his master's identity?

When a radical group called The Watchdogs emerges with plans to eliminate the Inhumans, Agent Mack and his brother become caught in the crossfire. Meanwhile, Simmons discovers a powerful chemical compound that could alter the future for Inhumans.