With Finch missing – kidnapped by his hacker nemesis, Root, Reese enlists Detectives Carter and Fusco to get his friend back, Meanwhile, The Machine never sleeps, disseminating a new number to Reese.

Carter tries to help Reese by engaging in mental warfare with the FBI; Reese has encounters with old and new enemies; Detective Fusco must protect supermodel Karolina Kurkova, the latest person of interest.