When the body of a young hooker is found in the district, Dutch's theory about a serial killer preying on prostitutes proves true. Aceveda launches an all-out effort to find the killer before he strikes again, giving Dutch and Claudette the full resources of the Barn for 24 hours and the help of the FBI.

While Vic continues his search for Corrine and their children, the Strike Team allow more drugs into Farmington through a corrupt connection. But when their latest shipment turns bad, they head to Tijuana to uncover the culprit behind the poisoned cocaine. Meanwhile, Dutch and Claudette try to track down the man responsible for "fire-necklacing" the leaders of two separate gangs.