Holmes and Watson join forces with the NYPD after a police officer is murdered. Also, Sherlock searches for the creator of a “recovery blog” who is posting personal statements he has made in sobriety meetings.

Holmes and Watson investigate the murder of a professional skeptic, a man who debunked paranormal, religious and scientific phenomenon for a living. The case becomes urgent when his homicide reveals a potential threat to homeland security. Also, Captain Gregson’s daughter and fellow NYPD officer, Hannah, asks Watson for help with one of her cases.

When Morland offers to use his influence to have Sherlock and Joan reinstated as consultants to the NYPD, Sherlock’s mistrust of his father makes him question his motivation to help. Also, with no work offers coming in, Watson wrangles a gig with the FBI investigating a triple homicide in a top secret research lab.

At the urging of Morland’s wealthy associate, Henry Baskerville, Holmes and Watson look into the death of his brother and discover that a witness saw the man chased to his death by a large, glowing animal.

As Holmes and Watson investigate a woman’s murder, they discover her death is linked to a piece of artwork that has ties to a crime that was committed when she was in college. Also, in the wake of a shocking personal revelation, Watson attempts to forge a connection with a recent client.

Holmes and Watson investigate a mass murder when a chef and his patrons are poisoned after dining on a tasting menu tainted with snake venom. Also, Detective Bell’s crush on a work colleague makes Holmes realize his and Fiona’s relationship is at an important crossroads.

Holmes and Watson get mixed up in murder and magic when they investigate the death of a magician killed while performing a classic stunt. Also, Watson suspects Bell is being targeted by the ex-husband of his girlfriend, Chantal, after a false allegation lands him the middle of an Internal Affairs investigation.

Detective Bell considers leaving the NYPD when he is recommended for a once-in-a-lifetime career opportunity. Also, Holmes and Watson are hired by a private client to investigate the disappearance of a young woman who led a double life online as a financial dominatrix.

Holmes and Watson’s deadly conflict with Sherlock’s former friend Michael intensifies when their newest victim looks to be the serial killer’s latest prey.

Holmes and Watson receive a shocking request to collaborate from their foe, Odin Reichenbach, when the tech billionaire asks them to test his new crime prevention system. Tasked with investigating someone the program predicts will soon commit a crime, the duo worries Odin will take drastic action before they conclude their inquiry.

Tech billionaire Odin Reichenbach inadvertently provides Holmes and Watson with a lead that could give them evidence that brings him to justice.