Derek's mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile, death row inmate William wishes to donate his organs to Bailey and Arizona's patient, as Owen and Cristina try to go on their first date.

Amelia and Link travel to New York to operate on a patient with a severe spinal deformity, but they’re in for more than they bargained for when Nancy Shepherd invites them to dinner at her home.