When Meg turns 18, Quagmire tries to make his move on her, but Peter tries to stop him.

Meg's exciting European adventure comes to a halt when she is kidnapped; Stewie and Brian embark on an action-packed rescue mission..

When Brian discovers that Carter Pewterschmidt’s pharmaceutical company is withholding the cure for cancer from the public in order to gain more profit, he and Stewie plot to expose the big secret that could change the world. Meanwhile, Quagmire reveals a hair-raising secret of his own.

When Meg learns her crush is gay and interested in Chris, she uses her brother to get closer to him.

As the Griffin family is preparing for Christmas, Peter tells his own version of the Nativity story.

Meg agrees to be Bruce and Jeffery's surrogate causing a pregnant Meg to annoy her family. But, when the couple fails to pick up the baby, the Griffins must take care of their new family.

Peter swaps lives with Supreme Court Justice Brett Kavanaugh and is forced to make a ruling on the constitutionality of gay marriage, meanwhile, Brett tries to become friends with Quagmire, Cleveland and Joe.

Lois becomes a stand-up comic, using real life stories about Peter as content; Peter tries his best to straighten his life out to avoid being ridiculed by Lois's act.

After successfully landing a plane, Brian and Quagmire go on a press tour. Meanwhile Chris and Stewie open a boutique pizza place.