Joey arrives in L.A. after his new agent offers him his choice of parts on two TV shows, and befriends his neighbor, Alex. His nephew, Michael, wants to move in with him at his new apartment, but Joey fears that this will upset his sister, Gina.

Gina is having trouble letting Michael live his own life, by constantly hanging out at Joey's place. Meanwhile, Joey is irritated by the notes his super leaves him. Also, the three of them go out to a bar where Joey and Gina try to teach Michael how to pick up women.

Michael is sick and Gina is delighted cause now she feels needed again and takes care of him. However, this bothers Joey, because now his sister is around all the time, so Gina offers him to crash at her place until Michael gets better. While staying at Gina's, Joey meets her secret boyfriend and confronts him. Also, an actor named Brian Michael David Scott repeatedly tricks Joey into missing auditions.

Bobbie gets Joey a job as a celebrity judge for the Miss Southwestern U.S.A. pageant, taking place in Las Vegas. With Gina, Michael and Alex in tow, he heads for Vegas. While there, Alex reveals her Celine Dion obsession, Michael teaches Gina how to count cards, and Joey accidentally sleeps with a pageant contestant.

Joey meets Deep Powder's executive producer, Lauren Beck. Joey worries that he may be fired after giving away a plot twist at a press conference. Alex, Gina and Michael decorate the apartment for Joey for Christmas.

Unable to decide who to take to the premiere of Deep Powder, Joey struggles to find tickets for Gina, Michael and Alex. Michael meets a girl and Brent Spiner and must choose who to leave with. Gina's date is Lauren's ex-boyfriend. Alex's date is a lesbian. Joey and Lauren kiss.

Joey is nominated for a Daytime Soap Award for his death scene on Days of Our Lives. (For the record, he was stabbed.) He is also presenting the award for Best Supporting Actress, and a problem arises when his inability to correctly pronounce one of the nominees' names leads to his saying the wrong name entirely. Meanwhile, Gina struggles with the fact that she is dressed unlike herself for the event.

As Eric moves out of their apartment and into one across the courtyard, Alex plants herself up in Joey's room with a pair of binoculars as Eric invites another woman over. After Alex goes to bed, Joey sees Eric kissing the other woman. Meanwhile, Joey's got problems of his own: even though he and Sara are allowed to see other people, he's not because he's too crazy about Sara. Trying to make her jealous, Joey discovers that she likes him as much as he likes her, and they decide not to see other people.

After asking Sara to move in with him, Joey freaks out. Sara freaks out too, and leaves without saying goodbye. Joey is heartbroken. On her first date in a long time, Alex accidentally offers sex to the guy, and Joey gets rid of him. While doing shots in Joey's bedroom and commiserating about the sad state of their love lives, Alex and Joey kiss! Meanwhile, Bobbie sets herself up with Michael at a Star Wars preview. When Gina confronts Bobbie about being attracted to Michael, Bobbie offers her a job.

Joey is on the set of "Deep Powder" but the fate of his character is still unknown. One extra, named Zach, tries to cheer him up in the hope Joey will help him (Zach) get a line to say. Zach will give Joey some tips about how to live as an actor in Hollywood. Jenna, a young actress-wannabe, moves in the building. She wants to meet Joey, the big star, but she first meets Michael who pretends to be Joey in order to land a date with her. Joey has an audition.

Joey bursts back in an audition room asking producers for one more chance (he entered a different audition room than the one he was in before!). He is determined to have a second chance and doesn't let the producers talk so they explain that he is in the wrong room. Not knowing what to do, producers start an audition with Joey. This leads to a funny audition with Joey saying lines for an action movie, when the producers read lines said by kids.(second part to a one-hour season premiere)

Joey faces an unruly child actor on his new movie. When push comes to shove, Joey takes matters into his own hands with interesting results. Meanwhile, Gina helps Alex get over her lagging love life.

Joey is preparing to shoot a big fight scene on the set. The director offers to use a stuntman instead but Joey wants to do his own stunts. Eventually, Chuck, Joey's stuntman comes in. Abby, the script reviser, has a chat with Joey because he doesn't follow script at all. Michael visits the set and he and Abby hit it off. Zach works Craft and Services on the set. Meanwhile, Alex is confused about her true feelings for Joey.

Alex teaches Texas hold 'em to Joe. The problem is that she makes up rules so he wins all the time. Thinking that he can play the game he accepts an invitation to play celebrity poker. Michael and Abby's relationship reaches new heights.

An old girlfriend of Joey's threatens to release an embarrassing tape. To prevent this from happening he must apologize to her on "The Ellen DeGeneres Show." Bobbie celebrates her 40th birthday.

Gina is planning a family Thanksgiving. Joey and Zach discover some ancient Native American artifacts on Joey's property and mistakenly give them away.