Teenage photographer Peter Parker is sent by the Daily Bugle to investigate a series of mystery lights in a wooded area outside of the city, when a sudden landslide forces him to swerve off the road and land in a tree.

On a blistering hot afternoon, Peter is walking to the house of a brilliant scientist, Doctor Smartyr, when suddenly he notices that the sidewalk, and most of the neighborhood, is turning to ice. Hearing desperate cries for help from Smartyr's house, Peter changes into Spider-Man and breaks through a laboratory window to find the frightened scientist being menaced by a towering ice creature.

Peter flies to Florida to find and photograph the Lizard Man. Spider-Man meets Dr. Curtis Connor's family. He is pulled underwater by the Lizard Man, but escapes.

Spider-Man is set up numerous times by Electro's robberies.

Spider-Man has been witnessed committing a robbery of the Midtown Museum.

The Vulture uses a sonic device in his head mask to control an army of vultures. After the Vulture beats Spider-Man, he holds the city up for a $2,000,000 ransom and J. Jonah Jameson blames Spider-Man.

An inventor named Henry Smythe reveals his plans to capture Spider-Man with a robot and get paid by J. Jonah Jameson for his efforts.

Dr. Stillwell creates the Scorpion on J. Jonah Jameson's behalf to capture Spider-Man. The Scorpion attacks Spider-Man, who escapes. However, the Scorpion's evil nature takes over as his strength increases which causes him to go after Jameson.

As Spider-Man examines the Goliath Diamond, the Sandman appears and swipes the diamond, with Spider-Man getting the blame as he is seen by the guards.

Spider-Man witnesses, and photographs, a giant metal-eating robot in Central Park.

The Green Goblin swipes Grandini the Mystic's witchcraft book, hoping to control demons of the Underworld.

Electro escapes prison, before Spider-Man can stop him, using a metal kite during an electrical storm to renew his powers.

Spider-Man faces off against Parafino, a wax museum owner who plans to make Spider-Man into his latest exhibit.

Spider-Man is keeping an eye on a train when the Rhino rams into it and steals the first component of a top secret weapon.

Someone has sent a one-eyed idol to J. Jonah Jameson. Jameson is hypnotized by the idol to steal his own money. Spider-Man finds the thief, but he escapes with the money.

Spider-Man attempts to halt the Phantom's activities only to be set up by him and his robot henchwoman Marie, who is disguised as a shop window mannequin.

Spider-Man saves a boat from Dr. Matto Magneto's attempt to crash it on the rocks by sabotaging a lighthouse.

Spider-Man gets into an embassy, sees the foreign visiting Prime Minister tied up and gagged, and fights someone impersonating the Prime Minister, but he is forced to retreat to find proof after being gassed by the imposter's cane and having his camera stolen.

Historic villains Blackbeard the Pirate, Jesse James, and the Executioner of Paris are committing robberies in New York City.

Miss Trubble, a book dealer obsessed with mythology, is owner of a magical chest from which she summons a succession of mythological figures, from centaurs to the Cyclops to Diana the Hunter-Goddess, to commit robberies of ancient artifacts on her behalf.

A scientist, Dr. Noah Boddy, renders himself invisible by means of a machine, then acts to avenge himself upon Jameson, who publically maligned his theory of invisibility.

Spider-Man battles an Arabian jewel thief, whose magical flute induces animals into attacking Spidey.

Reports of a legendary flying ghost ship, the Flying Dutchman, being sighted near Smuggler's Cove summon Spidey to the area, where his investigation into the phantom ship's appearance leads him to a cave in which he finds his sworn adversary, Mysterio, plotting with a pair of thugs.

When a Jekyll-and-Hyde poster comes to life at the soon-to-be-demolished Castle Theatre, Spidey visits the theatre and encounters mischievous Blackwell the Magician, who is trying to attract public attention to the theatre in hope of preventing its demolition.

Spider-Man's old enemy, the rampaging Rhino, is stealing gold bullion to mold an auric likeness of himself.

A bald-headed mastermind, the Plotter, employs two ridiculous criminals, Cowboy and Ox, to steal a blueprint to a missile.

Spidey chases the culprit in an attempted theft of jewels from a countess and is surprised to find that his opponent, dressed in a black Human Fly costume, also has the ability to scale walls and can cross thin wires between buildings.

Oil is being stolen in huge quantities by Dr. Von Schlick, a chemist villain garbed in a rubber, non-stick suit and armed with petroleum-based bubbles that he fires from his fingers.

The nefarious Vulture traps Jameson inside of a tower-clock and uses the well-informed Daily Bugle publisher as a source of information on the whereabouts of a visiting diamond merchant and the testing of military equipment—two prospective heists for the greedy bird-man.

Life-like and substantial shadows of beasts are projected in various locations in New York City by the Phantom's new Shadow-Scope glasses to cause panic and enable the Phantom to effect unconstrained bank and jewelry store robberies.

Doctor Octopus imposes upon Dr. Smartyr's Nullifier rocket test and steals the ultra-powerful destructor missile.

While Blackwell the Magician is entertaining at the Castle Theatre, his house is invaded by the Green Goblin, who swipes some of Blackwell's props and peruses Blackwell's book of magic spells and incantations.

Dr. Curtis Conner goes missing in the Florida swamps after finding the Fountain of Youth. When Spidey investigates the scientist's disappearance, he discovers a fifteenth century Spanish conquistador, Ponce de León, who is intent upon keeping the magical fountain a secret.

Because he hates rock-and-roll for its having replaced classical music in the tastes of the masses, a fiddler with a deadly, sonic violin seeks revenge upon pop-music sponsor Cyrus Flintridge.

Under the guidance of Dr. Noah Boddy, the Green Goblin, Electro, and the Vulture join forces for revenge on Spiderman.

Art robberies are committed by an old enemy of Spider-Man, actor Charles Cameo, who can utilize masks and make-up to usurp any identity, including those of J. Jonah Jameson and Spiderman!

When the Scorpion, intent on vengeance upon Spider-Man and Jameson, escapes prison, he visits the laboratory of his creator, Dr. Stillwell, and drinks a potion that vastly increases his size.

Paroled from prison, the Human Fly Twins rob diamonds from an importing company, and one of them does this deed in a Spider-Man costume so that the guard, before being hit on the head from behind by the second twin, believes that Spidey is the culprit.

Student Peter Parker is labeled a "bookworm" by his peers when he declines their offer of a triple-date in favor of viewing a radiology experiment.

On his first night at work at the Daily Bugle, Peter overhears talk of a fake medicine racket engineered by a rotund mobster called the Kingpin.

A twisted radiation specialist gains illicit dominion over Manhattan's new and only nuclear power plant and uses a special ray to lift Manhattan into the clouds.

Roy Robinson, star football player, campus ladies' man, son of a wealthy chemical industrialist, is envied by Peter, who decides to use his spider-power to play football and outperform Robinson.

Investigating the disappearance of banks, Spidey finds a hole that leads to a maze of underground tunnels, through which Spidey undertakes a perilous journey in search of the lost occupants of the submerged banks.

A baseball diamond and the spherical, baseball-sized Optimo Diamond at the Cosmopolitan Museum are connected in this episode.

Mugs Riley, evidently escaped from prison, has duped the Molemen into following him again.

Giant, mechanical beetles are used by Manta to capture and enslave the peace-loving inhabitants of an island to mine a valuable ore.

In ancient Egypt, one of the most aggressive of evil magicians, Kotep, the Scarlet Sorcerer, is defeated in battle with an opponent, and his own demons strike him with a cursing ball of fire that puts him in suspended animation, his mummified remains lasting through the passing centuries and becoming an exhibit at a New York university and the object of a professor's obsession.

A giant plant escapes from storage in a house belonging to Prof. Smithers, a missing scientist. Spidey goes through a portal (located in the scientist's home) to prehistoric times to find some defense against the plant and meets Smithers, who tells to him that two radium gems in an idol in a nearby city, if ingested by the plant in New York, will disintegrate it.

Pardo is a sorcerer with the ability to transform himself into a giant cat with hypnotic eyes. He lures top New York City’s citizens and officials to a theatre with the promise of a spectacular show, then releases his feline alter-ego's power upon the hapless audience, intending to divest them of their wealth and sap the souls out of their bodies.

Peter is an exchange student in South America, flying in a charter airplane with a Latin American professor in the Andes mountains. The airplane encounters a violent storm and crashes in a jungle, and Peter changes to Spider-Man to assist the professor and the airplane's two pilots in leaving the jungle and returning to civilization.

On Jameson's orders, Peter, and Daily Bugle pilot, Penny Jones travel by small-engine airplane to the Antarctic Ocean to track a fallen nose cone and crash-land on an island with a superstitious, brutish, native population.

At a coffee house, Peter meets Carol, a girl with whom he has much in common; he does not realize to what extent that they are alike until he, as Spider-Man, catches Carol in the act of robbing electrical equipment and finds that she has powers identical to his.

Clive, an unbalanced movie producer, is determined to avenge himself upon critics and audiences who spurned his claim that the darkest human emotions could be filmed and physically released from a theatre screen.

A giant Martian warrior, who throws lightning bolts, comes to Earth to rob the planet of its gold.

Dr. Irving Caldwell has devised a helmet capable of levitating its wearer and is kidnaped by a villainous scientist, Dr. Zap, who wants Caldwell's helmet to duplicate for his own evil use.

Sophisticated diamond thief Dr. Cool and his henchman have heisted a fortune in diamonds and are at a deserted-before-dawn ice factory, planning to smuggle the gems through international customs by mixing the "hot ice" with large quantities of the ordinary variety.

Two robbers dynamite a bank safe and abscond in their car with millions of stolen dollars.