A woman kidnaps Artie and insists that he help her recover her brother... who was lost in an artifact-related experiment 12 years ago.

In the season two premiere, we pick up right where we left off. MacPherson has blown Artie to smithereens, and disappeared. Is Leena really a traitor? Where has Claudia gone? How will Pete, Myka and the Warehouse fare without Artie? What other havoc did MacPherson wreak when he was alone in the Warehouse? And is there yet a new villain on the horizon?

As the Warehouse team prepares to celebrate the holidays in snowy South Dakota, Pete and Myka are called upon to hunt down a malevolent Santa Claus. Meanwhile, in time for Hanukkah, Artie and his estranged father, Isadore Weisfelt reunite after 30 years.

Pete, Myka, and Claudia set off to rescue their loved ones when Brother Adrian sends them deadly artifacts. Meanwhile, Mrs. Frederic and Steve travel to Rome and learn Adrian's dark secret.