After the murder of a suspected carjacker the team discovers that he may have been involved with a formidable drug lord and was suspected of drug running off Miami's shores.

Horatio's son goes missing when a prison transport is attacked. Upon learning the identity of Kyle, he is targeted in order to get at Lt. Caine, who must find him before it is too late.

Meanwhile, Ryan causes tension with his former colleagues when he is hired as an expert witness for the defense.