Four years ago, Sam and Dean helped a woman named Nora exorcise a demon that was systematically killing women in a small town. They managed to save a postal worker, Jeffrey, while vanquishing the demon, but now it seems the black-eyed monster has reared his ugly head and returned for a second helping. The brothers visit Jeffrey, who has been locked in a psych ward since the incident, to see if he can remember any of the demon’s plans while he was possessed.

Sam and Dean investigate a bizarre murder in a college town. Close on the tail of their suspect, they bust into an apartment to find two dead bodies and a laptop cued up to some disturbing video footage.

Castiel reappears in Sam and Dean’s life and tells them Crowley has unleashed several demons into a small town in order to find Lucifer’s Crypt, which holds a valuable relicts. While interrogating a demon, the three discover Crowley has been torturing Meg, who knows the location of the crypt.

Sam and Dean are reunited with Castiel as they are digging through the Men of Letters' files. They stumble upon an film which could be the key to completing the third trial. Metatron enlists Cass to mull over problems at home.

The angels are embroiled in a bloody civil war, and Castiel is swept up in the conflict. Meanwhile, Dean realizes that Ezekiel is not who he claims to be and tries to warn Sam with dire results.

Castiel investigates the mass slaughter of angels and finds a lone survivor and an old friend. Meanwhile, Sam and Dean capture Gadreel, and Metatron begins the ending of his story.

After attacking Gadreel, Dean leaves with Crowley to track down Metatron and kill him. Meanwhile, Gadreel takes Castiel into Heaven to try and break Metatron's connection to the angel tablet.

Crowley is worried that Dean, driven by the mark, is getting out of control. Sam struggles to escape from Cole. Hannah tries to convince Metatron to give Castiel his grace back.

When it comes to the Stynes, Dean decides to take matters into his own hands. Sam tries to come to terms with his decision.

Seen entirely from the point of view of the Impala, Sam and Dean go on a road trip to fight monsters and demons.

Now that he has Sam in the cage with him, Lucifer offers Sam a way out but it comes with a steep price. Dean and Castiel look into the angel smiting that could have killed Amara.

Amara shows Dean how she’s torturing Lucifer. Worried for Castiel, Dean and Sam come up with a plan to rescue him from Amara’s clutches.

Dean, Castiel and Mary have a lead on Sam and set out to rescue him. Dean is uncomfortable with putting Mary in danger but she insists on going along. Meanwhile, Crowley is tipped off that Lucifer has taken over the body of rock star Vince Vicente.

Lily Sunder steeps herself in black magic, honing her powers for over a century, waiting to exact revenge on a band of angels that murdered her family. Sam and Dean must work quickly to stop Castiel from becoming her next victim.

Sam and Dean begin to explore what Jack is capable of doing with his powers. An unexpected visit from Donatello alerts the boys to the fact that Jack will need more protection than the Winchesters can provide. There is a new Prince of Hell in town, Asmodeus, and with Lucifer out of the picture, he sets his sights set on Jack.

Sam and Dean devise a plan that will save innocent lives. Meanwhile, Jack continues to wrestle with the consequences of his decisions.

Sam enlists everyone’s help in trying to track down Dean, who can literally be anywhere. Meanwhile, Castiel may be in over his head after meeting up with an unreliable source. After being drained of his grace, Jack is adjusting to life as a human, learning new skills and figuring out how he fits in to this world of hunters.

Sam and Dean must figure out how to stop the bloodshed when Donatello, who, in his current condition, is inadvertently scrambling the order of future prophets. Nick comes face to face with his past.