After NCIS fails to locate a mole in the department, Under Secretary of Defense Corbin Duggan insists on new leadership and takes over the Los Angeles unit from Hetty and Granger.

The team travels to Syria to apprehend a High Value Target where one team member is severely injured when the mission goes awry.

The NCIS LA team investigates an abduction case while down two members, with Hetty being held in D.C. for questioning, and another still in the ICU following the mission in Syria.