Susan and Mary switch Johnny and Hugh's brains after the two make a bet that involves taking on each other's lives.

Susan and Mary purposely turn themselves into babies while the parents are out, and Johnny has to keep them safe from the irresponsible babysitter Gil; this interferes with a party he and Dukey had been planning.

Susan and Mary make fortune cookies that come true, and Johnny sells them with the typical drastic results.

Johnny and Dukey get framed for stuff that Johnny and Dukey look alike robots (which Mr. Black and Mr. White made) do around Porkbelly.

After getting his 99th detention, Johnny learns he must perform 99 good deeds or he will be sent to military school.

Johnny goes to the beach to surf, but there are no waves, so Susan and Mary build a wave making machine and special surfboard for him.

When Susan and Mary turns Johnny into a fish as part of one of their experiments, Hugh flushes him down the toilet by mistake where he ends up in the sewer, and he has to swim for his life when he runs into an alligator.

Johnny, the twins and Lila realize it’s Father’s Day, and they don’t have a gift. They try many disastrous attempts, making Hugh wish they had never remembered!

Johnny uses his sisters' genetically altered rat for a school project, only to have it stolen by a desperate circus owner to save his failing show.

Aliens from a meat-themed planet ask Johnny to protect their home world from Dark Vegan who wants to destroy it out of frustration because of his failure to make the perfect toast.

Johnny stays up half the night to watch a six-hour Halloween monster-movie marathon, then steals his sisters' dream machine (thinking it to be an alarm clock) so that he will be able to wake up in time for school the next day; however, he has nightmares during the night which the device brings to life.