After being jailed for solving another mystery, the Mystery Inc. gang stumbles upon another mystery: a gruesome monster lurking underneath the town and cocooning everyone who comes near in green goop.

Fred becomes the target of a high school crush when new girl Alice May falls for him. However, Alice May is actually a ghost with a reputation for taking guys with her and making them disappear forever.

A monster called the Fright Hound starts attacking Crystal Cove and people believe Scooby-Doo is behind it. Could Scooby be the one attacking the city or is someone setting him up?

When the entire town of Crystal Cove is taken over by Aphrodite's love spell, only Scooby-Doo and the recently-escaped Professor Pericles can save the gang from the spell and solve the mystery. But does Professor Pericles have ulterior motives?

Velma and Hot Dog Water go to Russia on a mission for Mr E, and bring back an old house which springs legs and runs rampage over town. Meanwhile the gang are looking to replace Daphne and Velma suggests Hot Dog Water.

Gary and Ethan are attacked by the Dark Lilith on Mount Diabla and lose the soccer team's lucky soccer ball.

Hebediah Grim, a pilgrim monster is targeting, attacking and judging certain women of Crystal Cove at the lover's hot spot, Lover's Lane.

The heroes must work together to realize that their love for each other is the true Heart of the Jaguar.