During an equestrian show, a young girl falls from her horse and is complaining of strange symptoms which makes Hank believe her father is hiding something. Elsewhere, Divya weighs over telling her dad the truth about her job, and Hank meets Jill's ex-husband.

The behavior of Tucker's best friend causes him to suspect the worst, but Hank realizes a medical condition is to blame. Meanwhile, Divya treats a woman who fears her job as a winemaker is on the line when her symptoms hinder her palate.

When the purveyor of a popular Hamptons food truck seems quickly corrupted by his success, Hank puts together his odd behavior, and pinpoints the cause of his symptoms.

Hank and Emily care for a patient together but disagree on the course of treatment. Meanwhile, Evan concocts a cyber retaliation plan against Emily.

Ken "Killer" Keller hosts a charity football tournament on his estate and invites Hank to play along. The contest gets fierce as Keller gets injured and Hank must put his competitive nature aside to treat him.

When a mysterious illness overcomes the members of an up and coming rock band, Hank and Divya have to work together to find the cause; but Hank struggles with trusting Divya after her near fatal prescription error.

Hank & Evan's father Eddie makes his return to the Hamptons and schemes to bring his boys back together. Hank has a new patient who is participating in a zombie race for charity. Evan also has a new patient, a retired biochemist with a possibly sinister past.

HankMed treats a polo team owner; Divya struggles with dating; Evan worries about a meeting of the in-laws.

Hank continues to treat Don and becomes more involved in the lives of Don and Molly; Divya tends to a young conductor, whose passion for music may be harming his health; Evan confronts obstacles in his new political venture; and Paige sees a new side of Blythe.