The Odyssey 5 team tries to locate Professor Naran Chandra, an artificial life researcher who in the original timeline will commit suicide at a lecture 8 days from now, right in front of Kurt. Examining the files on Chandra's computer, they find that Chandra discovered a computer lifeform loose on the Internet that apparently evolved on its own from experiments in Chandra's lab and has now become "Sentient".

Meanwhile, noting how mature and responsible his behavior has suddenly become, Neil's girlfriend Holly talks about taking their relationship to the next level.

Sarah and Angela's investigation of the patients given "gene therapy" by Dr. Barantz leads them to discover some living tissue that appears to have been bio-manufactured in a chemical vat. Then, when they finally meet the frightened Dr. Chandra, the team discovers that one of his students is actually an inhuman creature made from this same nearly-indestructible tissue.

When a top prosthetics researcher is found dead, Neil receives an anonymous e-mail telling him that the man was murdered by the "Synthetics" whose existence the Odyssey 5 group has discovered, which it says are the physical manifestations of Dr. Chandra's "Sentients". It claims that they are now after the researcher's six-year-old niece Stevie, all because of a ""cybiotic interface"" he was working on which would allow computer technology to control organic systems. Visitng Stevie's teacher, they find out that she is deaf and received a cochlear implant, which her uncle had been tinkering with.

Eventually, the team locates Stevie and finds out that her implant allows her brain to control a swarm of insects that have been fitted with cybiotic interface chips. But mysterious figures who may be Synthetics have relentlessly tracked Stevie to Kurt's place.