The Jeffersonian team rushes to prevent a viral outbreak while investigating the murder of journalist Mia Garrett after her infected body is found at a biohazard facility. When the mutated virus that killed Mia infects Jeffersonian intern Arastoo Vaziri, their only chance of saving him is by solving the murder. Tension and passion build as the team races against the clock to find the killer - and the cure.

Unable to relax on their honeymoon, Booth and Brennan decide to help a local detective solve the murder of a Nazi war criminal; Hodgins and Angela look after Christine.

A key witness turns up dead in a case for which Brennan is a juror, so the team works to discover what has happened.