The MPU searches for a Benjamin Franklin aficionado after he suspiciously disappears during one of his city tours. Meanwhile, a new forensic scientist is hired and the team attempts to manage her over-eager working style. Jason and Mike try to bond as new partners.

The MPU searches for a kidnapped tough-as-nails neighborhood watch captain. Jason enlists Wayne's help investigating the car bombing. Mike is concerned Nikki is keeping secrets from him.

Mike is taken back to his first unsolved case when the remains of an Amish man surface seven years after his murder. After he reconnects with the man's family, the wife of the man mysteriously goes missing, prompting a massive search and disclosing a web of deceit.

A popular travel influencer goes missing and the MPU race to find her as a hurricane rages and a state of emergency is declared. Mike and Wayne get closer as Helen connects with someone unexpectedly in the aftermath of Nikki's bachelorette party.

The MPU is on the case when a young boy claims his father was abducted by aliens as they were stargazing at a remote campsite. Jason and Nikki enlist Mike's help in getting access to Braun's computer files. Kemi and Helen partner up and venture out into the field.

When Wayne goes missing on the day of Nikki & Mike's wedding, the joyous festivities are put on hold as Jason and the MPU race to locate her and finally bring down Inspector Braun and his connection to the car bombing murders.

After a collegiate women’s rowing team goes missing during morning practice on the river, MPU deduce that their boat was sabotaged. When Kemi finds evidence connecting one of the girls to Irish mob boss, Charlie McGannon, Nikki confronts him as Jason and Mike interrogate a rival Polish mobster who may have intel on the girls location. Meanwhile, Jason explores his fear of commitment with Wayne, who’s now paroled.

When Nikki suddenly goes missing, MPU bands together and discovers that Raina, a criminal who Nikki put away, has escaped and is out for vengeance.

When an Army Lieutenant, and the wife of Houston’s old Army buddy, is kidnapped, MPU suspects a Major who the victim had reported for harassing women at the base. However, Jason and Mike learn that the victim and her husband were having marital and financial issues, leading them to uncover a dangerous and deadly weapons trade.

When Violet, a psychiatric patient, escapes her facility, Jason and Mike are shocked to find a letter from Jason and Nikki's daughter Sidney among her belongings. Mike and Jason go to her halfway house, they realize that she has been off her medication for days and are now concerned for her safety. Meanwhile, Helen takes her new relationship to the next level.

An accomplished playwright is kidnapped prior to a local theatre's grand reopening. MPU discovers that the victim and her partner had received a video threat ordering them to shut down the troubled theater, which had previously been severely damaged in a fire decades earlier killing 87, or the playwright will be burned to death. Meanwhile, Jason asks Wayne to track down who's the father of Sidney's baby.

When a brewery foreman is kidnapped after arguing with his CEO over safety violations, MPU finds evidence that suggests that the victim was taken by competitors over a stolen beer formula. Also, Bennett’s ex, who is also Houston’s step-son, threatens to make her life hell for interrogating his client without representation.