Dom is killed in a helicopter accident that also severely injures String. Dom's niece, Jo, inherits and takes charge of Santini Air. The Company sends Locke to regain possession of Airwolf, he recruits Major Mike Rivers ,an Air Force pilot to help him find and fly the craft. Together they rescue St. John from a jungle prison and he and Jo round out the new Airwolf team.

A Japanese Kamikaze pilot who survived being shot down by St. John's father during WWII plans on restoring his honor by killing St. John and destroying a nuclear power plant.