Bron's favourite patient Bob Parkin is back in the ward with pneumonia. He is stunned and disbelieving when told his illness is probably HIV related, and he refuses to have an HIV test. Nor is he forthcoming on the possible source of the infection, and Bron suspects he genuinely doesn't know. Bron makes it her personal mission to convince Bob to have the test, so he can take advantage of the latest therapies and treatments. However, her job is not an easy one as he has adopted an ostrich approach. Bron learns about Bob's long lost ex-lover and sensing she might be able to shed some light on his illness, tries to track her down.

Meanwhile, Luke assists in performing a laparotomy on Margaret Quinell. She has several tumours and the consultant is convinced it is terminal cancer. Luke is ordered to break the news to Margaret, even before the results of the biopsy come through. He's surprised however, when Margaret is philosophical about dying, as it means she can join her late husband. Margaret's estranged son David turns up at the hospital unexpectedly, after having lost touch with his mother. Connor finds himself treading a difficult path as he cares for Margaret and tries to help David reconcile with his mother before she dies.

Jared is dismayed and angry to find out that Angie is back in the ward. She fell over following an overdose and has a cut to her head. Dr. Wu tells her that he has contracted Hepatitis B and C. In addition to his normal duties, Jared takes care of Angie. However, he takes things too far when he invites her to stay with him and Connor upon her discharge from hospital.

The arrival of two high-dependency patients from the Intensive Care Unit and an incompetent agency nurse increase the stress and workload in Ward 17. Despite his reassurances to Terri, Peter has trouble dealing with Raelene Gregson, a difficult patient who he blames for setting in motion the events leading up to his wife's death. Von feels betrayed when she learns a young woman deceived her about how she contracted her illness. Jared covers for an overworked colleague's mistake but a second error results in him filing an incident report. Bron and Luke's relationship is made public much to their friends' delight.

While Stephanie tries to adjust to the idea of being pregnant, she is assigned to nurse a dying woman who wants to hold on for the birth of her great-grandchild. Jared goes to bat for a young man with a cricket injury, appealing to Dr O'Hara to re-examine him when his condition takes a drastic turn for the worse. Peter steps in when Sophie's concerns for a patient go unheeded by Prof. Craig. The arrival of two student nurses to the ward adds excitement to the ward.

An English tourist and his wife are admitted after a serious car accident. She is in a coma and he is desperate to see her — in spite of his severe chest injuries, which mean that he cannot be moved. When the woman dies of her injuries, Richard Craig instructs Stephanie not to inform the husband which proves to be a difficult task given her close involvement with him. Terri's faith is tested when a convicted rapist is brought onto the ward. Jared fears he may have contracted HIV while giving First Aid to a Angie. Bron helps Bob to confront his prejudices during a visit to Outpatients while Jaz is courted by a cute young radiologist.

Terri's emotional equilibrium is tipped when an old flame and colleague, Dr. Mitch Stevens, returns to All Saints after a ten year absence. She is confronted with her past and he delights in stirring the pot. Jaz is forced to make a decision about her pregnancy while Terri and Steph have a confrontation over the issue. Jared sticks to his old-fashioned romantic ideas in his quest to win Samantha's affections. Connor's life is made difficult by a female truck driver while Ben is forced to deal with an emergency situation while on an abseiling course.

In an episode about dependence between friends, partners and workmates, dependence takes the form of teamwork, friendship and co-operation for some, while for others it is a reminder of a lack of independence. A street kid holds Mitch hostage in an attempt to abduct his junkie friend from Ward 17. Bron and Ben are faced with a complicated premature childbirth which tests Bron and brings up painful memories for Ben. Terri tries to help Peter cope with his trying day as a hospital out-patient. Connor suspects a budding romance between two patients. Von's Employeee of the Month honour garners her more unwanted attention.

The ward is abuzz with the news a female boxer is on the ward, suffering from concussion due to a knockout punch in training. Charlie and her trainer Jimmy are itching to get out of All Saints and back in the ring — she is not too keen on hanging around for a CT scan — even though Luke fears she may have a cerebral bleed. But Steph suspects there may be other factors behind Charlie's symptoms, and a urine test confirms she is pregnant. Terrified a pregnancy will mean the end of her boxing career, Charlie demands an abortion. There's only one hitch, Luke refuses to write a referral, claiming there is no medical reason for a termination.

While nursing Charlie, Steph realises the young boxers's views on pregnancy are not as clear cut as she initially made out — especially when Steph points out motherhood need not mean the end of her promising career. But even if Charlie is cleared of brain injuries, she still faces a terrible decision: abort the pregnancy or lose her big chance to crack the US professional circuit.

The best-laid plans of Terri and Regina start crumbling when an elderly patient dies only hours before her long-lost son arrives on a mercy dash from the UK. Flu-ridden Bryce Jones is devastated to discover his mother has just died, but a bigger shock awaits him when he views the body — it is not his mother. In his already weakened physical state the emotional upheaval is too much for Bryce, and he is admitted to Ward 17 suffering from pneumonia. When his condition worsens and Mitch eventually diagnoses advanced cancer, Regina decides it is time to bring some happiness into the unlucky man's life.

Ben faces a reunion of a different sort when his ambulance is hijacked by Jason Richards — a mixed up young man whose obsession with becoming an ambulance officer has developed into full-blown psychosis. Ben is stuck in the back of the ambulance with a critically ill patient, and needs all his wits to convince Jason to drive them to hospital before the patient dies. It is a race against time which Ben appears to be losing when the patient suffers a cardiac arrest. Ben knows the only way he can save the patient is by relying on Jason's assistance — but is it a risk he is prepared to take?

Connor and Bron are shocked to discover Jared has not yet had sex with his girlfriend Mel. Connor makes it his mission to get Jared laid, whether he wants it now or not.

Meanwhile, Steph's experiences with Charlie have forced her to re-evaluate her attitude to motherhood. It is the end of a long journey for Steph and she knows Ben will be overjoyed to hear she wants to start a family after all. What she did not bargain on is Ben dropping the biggest bombshell of their marriage.

Nursing Unit Manager Cynthia Murdoch has devoted the past 25 years of her life to the Sacred Heart Rehabilitation Unit attached to All Saints. But, despite her superhuman efforts, the place is rundown, understaffed, last on the queue for funds and generally under continual pressure from the administration.

Bron is worried about Ben. He has slumped into a depression since Steph's death and she is concerned he is not taking adequate care of himself. So concerned, in fact she has temporarily moved into his flat to keep an eye on him. Which is where Ben drops his bombshell; he has decided to transfer from active paramedic duties to a desk job at HQ. Bron is aghast. She knows this is an ill-considered decision borne of his depression, but Ben won't hear reason. He is quitting just as soon as he finishes the paperwork.

Bron's desperation to pay back her gambling debt to Luke intensifies when she is stuck nursing one of his patients, a woman in dire straits with chronic back pain and a resentful teenage daughter. Mitch and Jared nurse a young man who will do anything to make himself more masculine — even if it kills him. Ben and his partner must try and calm down a lottery winner with suicidal tendencies and Von finds herself in an awkward situation while caring for a fellow nurse.

While Ben and his new partner, Scott are trapped in the path of a deadly blaze, the hospital staff are crying out for a cool change. Terri makes a big decision about her future while nursing a man with severe burn injuries and Connor finds it difficult working with Bron after his attempt to woo her fails.