The lives of the Ward 17 staff are about to change forever when an emotional Sophie battles her father-in-law to retain custody of her two young boys. With her best friends being used against her in a seemingly unwinnable custody fight, Sophie, in her desperation, makes a drastic decision about her children's future. Bron becomes emotionally involved in the fate of a car accident victim and his young daughter. Jared is an unlikely ally when a patient returns to Ward 17 for an operation he is determined will enable him to walk again.

Having responded to the scene of Sophie's car accident, Ben is having difficulty coming to terms with the aftermath of treating people he knows. Sophie and her children have survived the head-on collision resulting from her impaired driving but her friends are even more shocked when her desperate actions the night before come to light. Refusing to lose custody of her children to the man who raised her husband, Sophie confronts her father-in-law from her hospital bed putting Terri and Peter in the middle of a siege situation that will change eveyone's life. Meanwhile, Bron's fundraising netball game disintegrates when some personal agendas come into play on the court and Von's New Year's resolution seems destined to go up in smoke. A comment in the OR results in a nurse filing a report against Luke for negligence.