Peter is pushed to the limit when his life seems to be falling apart and he considers taking drastic measures. Samantha and Jared suspect a son of drugging his father but their differing approachs to the case serves to highlight their different backgrounds. Ben decides he can't wait for Steph to come around to the idea of having children and makes a momentous decision. While running the ward, Steph sends the staff mad when she takes her study too seriously. Jared and Samantha's relationship is made public, much to Jared's surprise. Luke leads a group of students on rounds and Mitch find the proper motivation to aid a patient's recovery.

Jared and Samantha's relationship is strained after he finds himself unknowingly caring for her mother when she is admitted to Ward 17 for a hip replacement and he finally learns why Sam has been hiding details of her personal life from him. Ben and Bron clash when she doesn't follow procedure while dealing with a heroin-addicted mother at the scene of a car accident. Forced to file a report on the incident, Ben then accuses Bron of taking advantage of their friendship. Von finds herself in the middle of a love triangle as she tries to keep a patient's wife and mistress from meeting one another. Luke's patient, a recovering drug addict, refuses pain medication after surgery leaving Terri to seek out alternative treatments. Meanwhile, Connor celebrates a birthdayand another temporary ward clerk joins the team.

Mitch is forced to confront his fears when a cancer patient refuses treatment. He embarks on a campaign to make his patient change his mind but ending up drunk and alone, he bangs on Terri's door. Steph gets starry-eyed about a possible promotion when Joan recommends Terri for a new position as her replacement. Bron gets the "relative from Hell" when she finds herself under constant scrutiny by a patient's daughter during her ward shift. Meanwhile, Jared blames Connor when Samantha's mother takes a fall and Ward 17 is finally sent a charming, polite and quick ward clerk… but for how long?

It's a heartbreaking time for Samantha when her mother does not respond to treatment for pneumonia and a wound infection. She finds she cannot cope with her impending death and Jared is shocked when she drops a bombshell on him. When an eager young bystander rescues an alcoholic from a blazing warehouse, Ben suspects foul play while Bron learns that ego is a dirty word. Meanwhile, Mitch uses his voodoo skills to help a deluded patient.