Teenaged twins Alan and Brett Cameron [originally seen in episode 1.39, although not by these actors] suffer from cystic fibrosis and have been on a long waiting list for lung transplants. Their overall health has deteriorated recently with Alan bedridden at home with pseudomonas. Brett has the same condition but is not quite as acutely ill as his brother. Alan has been brought on to Ward 17 for treatment. The staff know Alan and his brother very well — they have been regular patients at All Saints all their lives, and they are extremely well-informed about their cystic fibrosis and its complications.

The twins are bonded in age, temperament and, most of all, their illness. Now, for the first time in their lives, they are going to be separated by something they never anticipated: good health. When a lung transplant becomes a possibility, one of them will have a ticket to health, leaving the other behind. This creates feelings of guilt, isolation and bitterness they never anticipated.

Meanwhile, Connor is having his own sibling problems. He has to decide what to do when Jared finally tells him he caught Connor's brother Greg injecting heroin in the bathroom. Connor's initial hope of helping his brother is shattered when he finds Greg stealing. But what can he do to help Greg when he won't try to help himself?

Steph is nursing Seb Connelly, a sixteen-year-old Aboriginal kid from a small country town. Seb has relocated to Sydney on a football scholarship and contract and is in Ward 17 after an appendectomy. The chance discovery that he has only one kidney could have terrible repercussions for his career.

Terri's excitement about living alone is counterbalanced by the potential hurdles in her new life away from the community. Fortunately Von is there to guide her.

Bron, who had apparently kicked the gambling demon, is in danger again. When Greg Costello steals her rent money she has to find a way to get some cash in a hurry.