When Michael reveals his escape plan to Sucre, Sucre chooses to be no part of it, and requests a cell transfer. Michael gets a new cellmate called Haywire.

Sara has been jailed for murder. Wanting to make an example of her, the government has sent her to a women's prison and she faces 25 years to life. Heavily pregnant and fearful for her life, Sara must survive by making an alliance with an old enemy... but she's a marked woman and various attempts on her life lead Michael to take drastic action.

Michael, Lincoln and co reunite to break out an increasingly vulnerable Sara.