It's Elani, Karima and Fezile's first day as interns at the Beyers Naudé Academic Hospital. A medical mystery baffles Veronica and Elani.

Sollie finds out that Veronica doesn't play open cards. Fezile asks Gustav to do the operation on his father instead of Jolene. Tyson and his mother receive devastating news.

Karima struggles with a difficult decision. A patient, Henk, disappears from the operating table while Fezile had to look after him. Louw is stuck in the elevator with a pregnant woman going into labor.

Elani loses a very dear battle at work and cannot handle the pressure of her daily occupation. Veronica and Sollie's mothers come to visit to try to save their marriage.

Louw and Karima get married and he does not adapt well to married life. Fezile performs a breast implant on a trans woman. Jolene's past catches up with her when she has to save her stepfather's life.

Jolene is forced to confront her skeletons when she is sent to drug rehab. Fezile's father loses his battle against all his health problems.

Elani tells her mother that she has decided to stay in South Africa after all, but is not ready for the consequences. Suzanne convinces Gustav to drop his feud with Jolene.

Elani moves in with Veronica and Jolene. A sick patient causes the entire casualty department to be closed. Gustav gets a big setback. Louw finally tells Karima the truth.