When ghosts wreck a popular co-ed's school social life, she dedicates herself to hunting them, which forces Danny to deal with a threat just a few lockers down the hall. Worse yet, Tucker has a crush on the girl.

Danny and Valerie Gray are forced to become ""parents"" to a sack of flour for a one-week school assignment. At the same time Skulker, ghost hunter extraordinaire, decides to pit Valerie and Danny Phantom against each other in a contest - with the winner earning the privilege of becoming his prey. When Skulker's orchestrated contest ends in a tie, he handcuffs Danny and Valerie and hunts them both through the Ghost Zone. In order to survive, Danny and Valerie learn to let go of their mutual dislike and cooperate with each other - which may just affect their relationship in the real world. Or, not.

Technus is back, with a new plan to beam himself up to a super satellite and take over the world, and he's going to use Axion Labs to do it. As Danny Phantom battles Technus, Danny Fenton begins battling his feelings for Valerie, whose dad is back in charge at Axion. Sam and Tucker are surprised when Danny confesses he's thinking of asking Valerie to go steady. Unfortunately, as Technus puts his plan into action at Axion Labs, Valerie realizes her role as ghost hunter is putting her family and friends in danger. Can romance work between two kids with secret identities, or will the ghost boy and the ghost hunter end up breaking each others' hearts?

Dani Phantom has finally returned to Amity Park. Having the trouble of dissolving into nothing worst than ever, she seeks the one person who can help her, her cousin and best friend, Danny Phantom! However, Vlad has been keeping track of her since her last appearance and plans to get his "little girl" back, by duping Valerie Gray into doing it for him. After finding Danielle, she uses her to lure Danny into a trap and now she has two Danny Phantoms trapped! Now stuck in the clutches of Valereie Gray, Danny must find a way to escape and save his cousin from being melted to ectoplasm by Vlad!