After an argument with their respective boyfriends, Spectra, Kitty and Ember join forces and use their powers to make all men vanish. Danny and Jack are fishing in Lake Eerie, the only place on Earth immune to the spell. Sam, Jazz and Maddie must stop the villainesses while Danny is out of town. Unfortuantely for Danny, Skulker is taking more time hunting Danny to prove his girlfriend how great hunter he is. Can Amity Park be saved without its hero?

As one of the weakest ghost in the Ghost Zone, the Box Ghost attacks with every "deadly box" he has in the human world, but is easily defeated by Danny. He then makes a plan: he will use "Pandora's Box", the most powerful box ever created, and will use the evil and deadly powers inside it to attack Amity Park. Now Danny must find the only one able to save the day: Pandora herself!

Danny wakes up wearing a strange headset in the Ghost Zone. He returns to Amity Park and discovers everyone is asleep thanks to the ghost of sleep, Nocturne, who is sucking up their dreams to increase his energy. Danny must wake his friends and sister in order to stop this threat.

Danny's class goes to a camping trip with Mr. Lancer and Ms. Teslaff to an abandoned place which is seemingly haunted. Soon reports of monster sightings and missing students have the whole camp shook up. Monsters start showing up and disrupting the camping trip. To Danny's surprise, these monsters are ghosts working for Walker, on the hunt for Wulf. Now Danny must save his old friend and his class from Walker!