The miracle drug, Hapna, now threatens to wipe out humanity. A chronic jail-breaker named Axel is asked to find the only man with a cure: Dr. Skinner.

Searching Skinner's house and interviewing his old colleague reveals a new lead. Axel and Leland go to Istanbul but have trouble with local thugs.

Chris is held captive on an arctic oil rig by Russian operatives. The team unites to save her, despite learning Chris was once a Russian spy herself.