On their way to a cheer competition, Ron and the cheersquad get stranded, but Ron soon realizes that the whole thing could be a set up from an old enemy.

Kim accidently turns Ron into a selfish jerk with a new haircut, all while two new villians begin their new evil hobby.

When Kim is tardy when going to class, she is sentenced to detention. Meanwhile, Drakken and Shego start their next evil plan.

When Kim's parents chaperone a school ski trip, she is greatly humiliated. Meanwhile, a mad geneticist threatens the trip.

Kim is forced by Ron to join the race for class president, but when they bring home a spoiled Prince who is in danger, he runs against Kim.

Ron realizes that he is not technically a man yet, but Kim tells him that he is. Meanwhile, Kim and Ron must stop a villian from stealing a special ring.

When Señor Senior Sr. becomes disappointed in the way his son’s villainy is handled, he decides to hire a tutor to ensure his son’s success; which turns out to be Shego. Meanwhile, a hopeless Kim is stuck on Home Economics with Ron but when Ron becomes an expert chef while Kim can’t cook a single thing, Ron is chosen to help Kim out. Can Kim overcome her predicament or is this one sitch that she cannot escape from?

Kim and Ron are taking Drivers Ed, which most of the students are nervous but Kim remains confident that she’ll do a good job. However, when she chokes up and fails the initial test, she soon learns that the pressure of the test is far greater than any foe she has fought. Meanwhile, Dr. Drakken has kidnapped a scientist who specializes in artificial intelligence, Kim gets a visit from an unexpected guest that may be able to help her out.

It’s career day and Kim expects to be paired up with her mother. However, when Bonnie gets teamed up with her instead, Kim gets stuck with a janitor who seems too dedicated to his job. Meanwhile, Ron gets paired with a secret agent and gets a plethora of unique gadgets to try out. However, with Dr. Drakken stealing a weather machine so he can flood Canada, Kim may just realize that her mentor may be more useful than she first thought.

When Middleton High School participates in a student exchange program, Ron is selected to go to a school in Japan while a student named Hirotaka is chosen to come to Middleton. Ron finds out that the school he was assigned to visit is a secret ninja school while Kim and Monique eventually start crushing on Hirotaka. However, when Lord Monkey Fist steals the Lotus Blade from Ron’s sensei, it’s up to Ron to save the day; though without Kim’s help.

Ron signs an unwilling Kim up for the school talent show after Bonnie announces her intent to crush any competition. Her plans to sing are interrupted when Wade begins acting erratically and orders Kim and Ron to recover teleportation technology from Professor Dementor. Technology, she suspects, that may have not been stolen after all.

On their way to cheer camp, the squad again finds itself at Camp Wannaweep for the Spirit Stick Competition. Kim deals with having an obnoxious Bonnie.

When Kim catches a cold from her brothers before a mission, she soon discovers that it’s hard to save the world when you’re not feeling well. Dr. Drakken and Shego exploit the moment to steal a laser from the research lab Kim is guarding. However, when Kim’s sickness begins to spread, a series of events occurred that not even she could expect.

Kim, hoping not to be landed with Ron as her science project partner, instead gets a brainiac who won’t let her do anything at all. Monique gets Ron and quickly becomes exasperated by his trademark laziness. Meanwhile Drakken charms DNAmy into creating a vicious Komodo dragon.

Kim catches a nasty cold from the Tweebs, but still accepts a mission to guard a mysterious machine. After Drakken and Shego steal the device, her mother insists that she stay in bed to rest while Ron and then the Tweebs take up her duties. By the time matters are resolved, everybody on both sides of the conflict has caught the cold.

When trying to save a scientist from Dr. Drakken’s secret arctic base, Kim and Ron are hit with a truth ray which forces them to speak the absolute truth about every issue. Kim soon discovers that this is a huge embarrassment while Ron is enjoying his newfound truth potential, but can they get through the day without causing themselves huge problems?

While trying to stop Dr. Drakken, Kim gets into a fight with Shego in which they accidentally get a microchip attached to each of them that can control their emotions. However, when Ron accidentally picks up the control device instead of Kim’s communicator, he thinks it’s a game and he inadvertently controls Kim and Shego’s moods, in which he puts on romance mode before he and Kim go to school. Ron must now deal with Kim’s sudden advances towards him while trying to determine what he should do about the situation, all the while Drakken is dealing with a suddenly love-stricken Shego.

When Kim and Ron go to stop Professor Dementor from stealing from a top-secret research laboratory, Ron inadvertently catches Dementor’s “Bondo-Ball” in his pocket, which he accidentally triggers later that day. When Ron rushes into Mr. Barkin and gets stuck to him, he rushes to warn Kim but discovers that she is already stuck to Bonnie. Now Kim and Ron must work with their enemies while trying to cope with what occurred to them and there’s still Professor Dementor to worry about; but will Kim and Ron gain any insight towards the life of their enemies through the ordeal?

When Ron is trying to prove he’s old enough to not be forced to sit at the children’s table at a wedding when he realizes that his evil cousin Sean will be there, he decides to find a date so that it would prove he’s old enough to sit at the more mature tables. However, when both Ron and Kim believe they shouldn’t go together because it would be awkward, Ron decides to try to be a bad boy after he sees an episode of “Agony County” on television because he believes they get all the girls. However, when Kim and Ron go to a villain convention in order to see what is going on, Ron and Drakken inadvertently switch personalities when a machine goes awry, causing Ron to become a maniacal madman and Dr. Drakken to become a kind spirited individual, Kim realizes that a bad Ron may be more than she expected.

After Kim constantly foils Dr. Drakken’s evil plans, he decides to try to take over the world through his brain washing shampoo “Lather, Rinse, Obey”. However, the shampoo sells horribly and after talking with Shego, he learns that items mentioned in hip-hop music usually sells quite quickly. When his attempts to persuade a star to use his produce in their song, he enters an “American Idol” type contest in order to become a star long enough to make his shampoo sell. However, with Kim on his trail, will she be able to foil his plan once again?

Junior attempts to rob the Tower of London, but accidentally tries to rob a movie set replica. Kim and Ron go to stop them and perform an extreme mid air stunt and the movie set's director offers them a movie, which they happily agree to. Kim now must deal with Heather, an actress who is going to be her in the movie taking her friends, and Ron has to deal with Quinn, an actor who is going to be him in the movie act completely opposite of him. All of this while they have to stop Junior who is out for revenge on the director for not putting him in the movie.

Kim investigates a string of celebrity robberies, but comes up empty-handed. Meanwhile, the tweebs enter Middleton High School as freshmen. Ashley Tisdale guest stars.

Ron comes home to unexpectedly find his new adopted baby sister named Hana Stoppable in his room. At the same time, he has to take care of a sack of flour for health class. Meanwhile, Kim and Ron team up with Yori to stop Monkey Fist yet again.

When the Fashionistas and Camille team up to steal secret designs from Club Banana, Kim, Monique, and the Fashion Police must stop them. Meanwhile, Ron and Barkin get trapped inside a shipping crate.

When Ron gets a scare when he thinks he is getting fired, his boss suprises him by making him watch his son instead. Meanwhile, Frugal Lucre gets let out of prison, and immediately goes back to Drakken. They soon begin a new plan together, much to Drakken's disgust.

Things get out of control when Ron and Bonnie become the homecoming king and queen. Now Kim has two problems to deal with – a missing computer expert and Bonnie making a move on her boyfriend.

High school graduation nears for the senior class, but Warmonga's return jeopardizes everything as Team Possible goes through their toughest odds yet to save the planet.

After both Kim and Drakken have been taken captive, Ron and Shego must race to rescue them from the clutches of Warmonga, Warhok, and the other invaders. All of the main characters must now band together to save the planet that they call home.