A blind man is led into the middle of an intersection and left to be run over by his German Shephard. While picking up Mel from an aborted date, Cole senses the presence of one of his prisoners, and soon determines the German Shephard has been taken over by one of the last arrivals on the train: Medoran, Zin's bodyguard. Zin is putting his bodyguard to use, killing a councilwoman who stands in the way of his desire to have a district of Chicago rezoned. Cole tracks down the dog, which can shift forms into a werewolf-like humanoid, and manages to capture it.

With Nestov's help, Cole captures Vesser, who was using Nestov to hire supplies for a theft. A Desserian thief named Zareth is planning to steal something during an art exhibit. Through Det. Bruno, Mel manages to wrangle an invite for her and Cole, although Vic thinks she was using it to set up a date with him. Cole is unable to locate Zareth, and then an assault team led by Max break in. Cole doesn't believe Max is Zareth, and sneaks off to investigate. Bruno is shot and critically wounded. Mel manages to grab a cell phone and call for help, while Cole discovers that the brunette who was the curator's escort is Zareth. Zin set up the theft with Max and his men so that Zareth could break into a vault and steal an ancient Egyptian statue containing an alien map of some sort. Cole intercepts Zareth but she fends him off with her chameleon powers and a can of nitrogen. Zareth shoots Max so that the police can arrest his men, providing a distraction for her to escape. However, Cole uses hy

Cole interrupts a mob transaction between Jimmy and one of the prisoners, Trepp. Cole captures Trepp and escapes, but realizes that Zin and the mob are connected somehow. Despite Mel's reluctance and with Nestov's assistance, Cole takes on the face of an obscure 20's mobster and goes undercover, using his techno-gizmos to give himself a cover story with Tommy, the head mobster. Zin and Tommy's gang are rivals, with Zin taking over their territory. Despite Jimmy's suspicions and Vic's interference, Cole manages to find out that Zin is drilling 300' down in several buildings in the downtown area. Tommy and his gang end up in jail, leaving Cole with another piece of the puzzle.

One of the prisoners, a Desserian named Suudor, is duplicating famous serial killers like Gacy, Manson, and the Boston Strangler. Tracking him, Mel and Cole find he's taken a ticket to England. Coincidentally, Jess is in England with her ex-boyfriend. Suudor is planning to duplicate the acts of the most famous serial killer of all time: Jack the Ripper. Worse, one of Zin's operatives is helping Suudor and gives him pictures of Jess and Mel. Suudor escapes Cole at a hospital and prepares to close in on the women... (to be continued...)

Mel tries to dissuade Jess from meeting with Hunin in Whitechapel to get engaged, but oversleeps. Meanwhile Cole tries to track Suudor and runs afoul of Jager, one of a set of bonded Orsians. He defeats Jager but alerts Parker, his twin-Orsian. Suudor tries to kill Mel and Cole catches up to him but is flash-frozen by Parker. It was a trap to lure Cole in. Suudor goes to kill Mel but Cole manges to recover enough to freeze time, rescue her, capture Suudor, and escape. It turns out Parker and Jager were not any of the escaped prisoners and that Zin already had an organization on Earth prior to the escape. And that Zin had some reason to lure Cole out of Chicago and to London...