Brock and the Venture family are on the run from the Law, the Monarch, Sgt. Hatred and the entire O.S.I.! Only bald ingenuity and an unlikely ally can possibly save their necks from the deadly noose tightening around the Venture Compound.

Someone is capturing heroes and villains and taking them to a super death camp. The forces of good and evil must join forces to stop their mysterious captor.

Team Venture, Conjectural Technologies and the Order of the Triad come together as Dean and Hank prepare to face an obstacle that is more intimidating then anything they have confronted before: a prom to celebrate their "graduating" high school, while Dr. Venture throws out all the stops to bring the twins the best dance $500 can buy. But when things go awry, the greatest battle in Venture history looms as two old enemies - the OSI and SPHINX - clash once again.

Space. The final frontier, where no one can hear you scream, revenge is only served cold, and the drinks are comped in the casino. Join the Ventures–and pretty much everyone they’ve ever crossed paths with–as they rocket to the Gargantua-2 space station for an epic, hour-long adventure that will change the Ventureverse as we know it forever.