Diane has thousands of tumours all over her body.

Irais's kids are bullied because of the growth on her head.

Belinda's lump on her neck causes her immobility. Nick foolishly removed a lipoma at home.

April is covered in bumps disfiguring her arms. Genner is in from the Philippines to treat his bumpy nose.

Jen’s growths on her ears give her depression, pain and vertigo. Gerald has a lump on his middle finger.

Gerald is back to see Dr. Lee about his finger bump. Vinnie has a big birthmark on his neck.

Taylor has a large bump at the base of her spine and Noelle wants her stretched ears repaired.

All new pop-up facts and secrets are revealed as renowned dermatological surgeon Dr. Sandra Lee removes life-altering growths from her patients' skin.

Dr. Lee assists Matt with the tumours growing all over his body.

Inoke has a possibly life-threatening bulge on his shoulder. Delano returns with his back lump.

Melissa tries to cover a lipoma with a sweatshirt and Amber's ear keloids have taken over her life.

Leonard has a bump on his arm that looks like it's breaking through the skin. Jess got a lump on her bum after falling down the stairs.

Gerard has nearly 100 lumps all over his body. No one has been able to help Gina with her bloody lesions.

Dr. Lee encounters the largest lump she’s ever seen. Plus, Amber suffers from a debilitating skin disease.

Traci has bumps all over her face, and Ravon has a growth that dangles near his genital area.

Dr. Lee examines a man’s suspicious eye growth, and Nicole has lots of large bumps on her neck.

Barb seeks help for a heart-shaped lump on her back, and Hilda has bumps all over her eyes.

Lisa gets treatment for a horn on the back of her head, while Victor has a big lump on his chest.

Patrick has huge bumps covering his nose, while Joe suffers with a lump on his forehead.

Jose has a baseball-sized head lump, and Ken is covered in painful bumps.

Jackie has a giant bump on her right shoulder that recently tripled in size.

34-year-old Che’Re has a giant bump on her face that keeps growing bigger.

Dennis wants to remove the large bump on the back of his head, and Juan’s nose is covered in bumps.

Audrey seeks help for the golf ball-sized bumps all over her body.

John has a large lump on his neck that feels like a squishy tennis ball.

9-year-old Yaellie has itchy and scaly skin all over her body.

Joanne’s forehead growth has held her back, and Mike has a soft head bump.

Ed wants a lump removed before his girlfriend gets out of prison.

JD has a pear-shaped ear mass, while Julie hopes Dr. Lee can remove her large back growth.

Veronica wants to be free of the bump on her butt, and Marty hopes to remove his shoulder growth.

Brittany's genetic condition causes head-to-toe bumps. Plus, Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Stacey's shoulder growth prevents her from being the playful teacher she once was. Matthew worries the rash on his shin may be dangerous.

Jaclyn has a distressing head lump. The growth between Shane's eyes could be dangerous. Brittany seeks answers about the sores on her body.

Lattyse’s mysterious growth gives her headaches. Robert has a tomato-sized growth on his bottom that causes him pain. Sharon has a smelly, squirting cyst.

Keke’s bumps make her embarrassed to be intimate with her husband. Corey has been labelled a devil worshipper because of his forehead growth.

Monica returns in the hopes that Dr. Lee can remove more of her face growths. Ken has tried to remove several large head cysts on his own.

Corey has a growth hanging from his bottom that has been growing for 10 years. Adam has semi-circle of cysts on the top of his head.

Terry’s nose growth has prevented him from meeting his grandkids. Remi has alligator-like skin and Austin has an embarrassing birthmark that he cannot hide.

Roger has huge growths on his nose that drip pus, attract flies and are so big he can barely breathe. Sisters Sandra and Jessie bonded over their face bumps.

'Tis the season for squeezing as Dr. Lee pops her way through the day! They'll have their hands full during one of their busiest days of the year.

Roger returns with his gigantic nose growths in the hopes that Dr. Lee can help. Christine has lost her essence due to a large shoulder growth.