When Chief of Internal Medicine Dr. Amy Larsen suffers a catastrophic brain injury, her life is turned upside down. Still determined to once again practice medicine, she charts a new path forward, ready to face whatever obstacles stand in her way.

Amy, allowed to return to work under strict guidelines, teams up with TJ to treat a patient suffering from mysterious liver problems. Sonya and Jake help an elderly couple navigate the final chapter of their love story.

It’s a race against time as Amy and Jake try to uncover the cause of a unique patient’s worsening condition. Gina treats a quirky hypochondriac, and Amy makes a shocking discovery about her pre-accident love life.

Amy, finally allowed to practice medicine again without supervision, struggles to diagnose her most complicated patient yet: TJ’s Dad. Sonya and Jake treat a single mom who’s reluctant to stay in the hospital. Richard tires to contain the truth about Dixon.

A mass casualty event requires all hands on deck at Westside Hospital. Amidst the chaos, Gina deals with a devastating revelation and Amy’s forced to confront her demons.