Patrick Kent, a Vice-President of a New York investment-banking firm, vanishes from a San Diego airport, only leaving behind two empty suitcases.

They search for a retired U.S. Army officer who has disappeared right after a dinner that was given in his honor by former members of his Vietnam platoon

A missing-persons case becomes a criminal investigation when, after a recently engaged woman disappears, it turns out that she was running a confidence scheme.

When Sam helps Martin search for his missing and terminally-ill aunt, they discover that she's been using her nursing skills to assist other dying patients in committing suicide; his father's Alzheimer's diagnosis prompts Jack to attempt a reconciliation.

The team search for a nurses' aide who who disappeared from a rural road while changing a flat tire, only to discover that she is actually a fugitive wanted for the bombing of an abortion clinic.

Bryan Parker is questioned by the FBI after being found alone on the road by a police officer, his hand bandaged. He tells them about a young boy his father had abducted, and soon the team is searching for Todd. The search initially goes nowhere, and Sam continues to question Bryan, but they get a lead when Bryan identifies a snapshot of the boy that reveals his identity to be that of missing boy Daniel Ellison. It isn't long before the squad realises that Daniel isn't the first boy that Parker grabbed, and follow his past to find him and the missing boy.