Expectant mother Laci Peterson vanishes in Modesto, California, on Christmas Eve 2002; while the community desperately searches for her, the police narrow their focus on her husband Scott, and the case becomes a national media sensation.

Laci's body is discovered, and Scott becomes the most hated man in America; the whole world tunes in for Scott's trial, and he is convicted of murder; now, Scott shares what was going through his mind and the thoughts that haunt him.

For 20 years since Scott's conviction, those closest to the case have been uncovering new evidence and investigating alternative theories of what may have happened to Laci on December 24, 2002; now, the Los Angeles Innocence Project joins the fight.