With Jiro’s disappearance, Yuri supports Otoya’s induction into the Wonderful Blue Sky Group as IXA’s official user. But when they plan to seek out her mother’s lost ring, Otoya finds himself suffering memory loss after a battle with Rook, when Maya, the Fangire Queen, arrives and claims to be Yuri! Meanwhile, in 2008, Wataru finds Mio has distanced herself from him after an encounter with Bishop, another member of the Checkmate Four!

Continuing to take advantage of Otoya’s memory loss, Maya attempts to learn more about human love as Otoya searches for the lost ring. But when Yuri finds them, she may have to be the one to explain it to the Fangire Queen! In 2008, Wataru worries about Mio’s whereabouts as she hides from her duty as Queen. With Bishop demanding her obedience, she turns to Wataru for help, but gets ambushed by the Spider Fangire, who has stolen the IXA gear!

Bishop begins the preparations for the wedding of Taiga and Mio, but Mio admits she is in love with someone else and can’t go forward, enraging Taiga. Not realizing it is Wataru she loves, Taiga enlists the help of Wataru, who is himself blind to Mio’s true feelings, to try and determine who she has feelings for. When she meets with Kengo in the park, Taiga confronts her as Kengo attacks Wataru, but Jiro brings Watary back to Castle Doran to observe a mysterious sword embedded in the wall, said to be extremely powerful…

Mio reveals her feelings for Wataru as Taiga lurks nearby, discovering the truth for himself. As Wataru basks in his happiness, Taiga confronts Wataru and invites him to Mio and Taiga’s wedding, telling Wataru he’s always been weak. Jiro brings Wataru back to Castle Doran, suggesting he try once more to claim the Zanvat Sword by wishing for its power from his heart. Meanwhile, in 1986, Yuri confronts Maya, but Maya refuses to attack, knowing she’s taking something far more precious from her…

When strange magical creatures including something resembling the Minotaur begin to attack in Toriizaka, they are all confronted by a man with a strange ring and belt calling himself "Wizard".

While trying to battle the Phantom Hellhound, Haruto is accosted by Shunpei Nara, who wants to be a magician just like him.

Shunpei Nara decides to go on live television to show off his burgeoning magical powers while Haruto tries to deal with both the young man and Hellhound's attempts to attack him now that it is clear Shunpei is a Gate.

After a mysterious white Garuda delivers a new Magic Ring and stone to Omokagedo, Medusa sends out Ghouls to attack a young boy who is suspected of being a Gate as Haruto finds himself facing Phoenix.

After finding out that Hiroki is the son of his old friend Mikiko, Haruto suggests that he watches over him until the Phantom case is solved. However, Phoenix attacks Mikiko instead of bringing Hiroki into despair and when Haruto realises this, he searches for his father.

Around Christmas time, Misa locates a new Gate in the form of a young man with a Yankee fashion sense named Tatsuro, and Haruto must get to the bottom of what his hopes are in order to protect him from becoming a Phantom.

Both the Phantoms and Haruto keep an eye on the mysterious young man Kosuke Nitoh.

When Rinko disappears and all that's found is her bloodied ID, Haruto seeks out her attacker, unaware that Yugo has disobeyed Wiseman and acted on his own volition, with Rinko in the way of his goals.

With Rinko's life on the line, Haruto readies himself for a battle with Phoenix who has become more powerful, despite Kosuke's intention to take Phoenix's magical power for himself.

Kosuke is meeting an archeologist to get the new Beast Color and a gun-like weapon. However, the BeastDriver is suddenly stolen. To make things worse, Gremlin and a new Phantom appear to defeat the magicians.

Kosuke must find a way to retrieve his Beast Driver and Wizard Rings back from Spriggan while Chimera tells him about his chance to eat him alive.

Haruto finds he must battle White Wizard on his own for Koyomi's sake after Kosuke uses the last of his mana to disrupt the Sabbath. Elsewhere, Yuzuru and Yamamoto come to their senses and plan to fight alongside Mayu and Haruto for Kosuke.

With Gremlin in possession of the Philosopher's Stone, Koyomi dies. However, Fueki says that the light in Haruto's heart is the true Philosopher's Stone. Meanwhile, Gremlin, now evolved, goes on a rampage, and Kosuke cannot battle to save anyone or even himself from the monstrous Phantom.

After his defeat at the hands of Bravo, Kaito believes he is no longer strong enough and seeks out a new strength. While Kouta seeks out a new job, Mai finds herself trapped in the Helheim Forest again, forcing Kouta and Mitch to go and rescue her.

Kouta and Mitsuzane must hunt down a fully manifested Inves that is randomly attacking people in the city while also dealing with keeping up their Beat Rider ranking.

Kouta and Mitsuzane begin to postulate on the identity of the white Armored Rider who seems to be destroying all evidence of the Inves entering their dimension. To try to figure out what should be done about both the Inves and the white Rider, Kouta decides to consult with the other Armored Riders

As the Lockseed gathering "game" begins, Baron and Bravo fight between themselves, while the white Armored Rider, Kamen Rider Zangetsu, investigates the infiltration into Helheim Forest. Meanwhile, Kouta, who has also entered the forest, decides to track down the white Rider and finds the base of operations that may be the cause for the tears into Helheim Forest opening on their own.

Emu, a clumsy pediatrics intern takes young Sota, who is suffering a mysterious illness, to the announcement event of the latest "Mighty Action X", Sota's favorite game. Emu became a medical doctor in order to save someone's life because his life had been saved once through surgery.

However, a mysterious virus emerges from Sota's body and the event turns into chaos. Emu hears from Asuna, an employee of the Ministry of Health, that transforming into a Kamen Rider can save the patient. Emu takes on this "operation" and inserts the Mighty Action X Gashat into the Gamer Driver, transforming into Kamen Rider Ex-Aid!

Becoming Kamen Rider Ex-Aid, Emu now must serve as both a pediatrician and a member of CR. A gifted surgeon named Hiiro Kagami comes back from the United States and is not only the son of the director, he’s also Kamen Rider Brave. This results in a clash of ethics when it comes to dealing with patients.

A hospitalized patient showing two symptoms of the Game Disease has appeared. Emu and Hiiro transform and succeed in separating the two Bugsters from the patient. But Genm appears again to interfere, letting the Bugsters escape.

Taiga manages to capture the Bugster which escaped in the last episode and obtains the Jet Combat Gashat, holding the Bugster, and thus the patient, hostage in exchange for the other Riders' Gashats. When they arrive to challenge him, he decides only he is needed to fight the Bugster, and tries to destroy Ex-Aid and Brave.

With the Bugster infection spreading rapidly, the authorities can't hide the disease from the public anymore. After Kiriya's death, Kuroto starts targeting the other Kamen Riders for their Gashats, but Parad approaches Emu, offering him a blank double Gashat which will allows him to attain a new level of power…

Ex-Aid, now as two, get into an argument about defeating Genm or the Aranbura Bugster. They both seem to be Emu, but Genm and the Bugster take this opportunity to escape. Emu reverts to his human form and falls unconscious.

Wanting to save Dr. Shirakawa, Emu asks Hiiro to perform a surgery on his cancer. He has his Gashat back and faces the Aranbura Bugster to also cure Shirakawa's game illness. Will the surgery succeed? What will happen to Ex-Aid?!

Emu finally learns of the horrifying truth that he has the game illness. The Bugster virus in him acts up and he collapses to the ground, though for some reason no Bugster has appeared...

Emu later wakes up in CR with his personality completely changed to that of "Genius Gamer M". When a new Level 30 Bugster emerges, Emu transforms into Ex-Aid with delight, and fights as if he were playing a game while no longer concerning himself with the patient. Just what has happened to Emu?

Taiga and Nico meet a high school student named Daisuke who is infected with the Bugster Virus and calls both Emu and Hiiro for their help. Parado suddenly appears and Hiiro faces him in his new form while Emu is hesitant on joining the fight.

Recently, Emu has been feeling a little worried. He is very quiet and hasn't talked much since Poppy Pipopapo suddenly disappeared. Just then, Hiiro is shocked by the sheer number of emergency calls coming to CR, all reports of the game illness! As the only CR doctors, Emu and Hiiro rush to the indicated locations, but what they find there is an unbelievable sight...

Kamen Rider Chronicle has already begun! Para-DX has joined the game and defeated the first round of the general players, giving them a Game Over as Emu watched them disappear before him. Kamen Rider Chronicle is being sold at an extremely fast rate, which catches the attention of the Ministry of Health. To avoid any form of confusion, Kyotaro Hinata orders a temporary halt on the actions of the doctors in CR. However, a game disease patient escapes from CR in an attempt to cure his own game disease, which leads Emu to chase after him. Then suddenly, Poppy Pipopapo appears before them with a new Driver and a Rider Gashat of her own…

Suddenly, the Gamedeus virus begins spreading through the streets! Masamune becomes Gamedeus Cronus and appears before the other Riders, as he summons Nico into the World of Kamen Rider Chronicle! Nico is the one who is qualified to challenge the Last Boss of Kamen Rider Chronicle as a Ride-Player, but it seems clear that Masamune is going to try to Game Over the player who is closest to beating the game in order to reset it. In an attempt to save her but unwilling to let the others follow, Taiga uses the Chronicle Gashats seized from patients and goes to find her. However, the other Riders cannot enter the World of Kamen Rider Chronicle! Just what will happen to Nico's fate?

Gamedeus Cronus has grown massive and become the strongest Last Boss! The Gamedeus Virus expanded and the pandemic has gotten worse. The Gamedeus Virus can now be transferred from person to person, turning the infected into Bugster Virus foot soldiers! Two Bugsters witnessing this symptom, Parado and Poppy Pipopapo, decide to take action. "There is something that only us Bugsters can do…" Poppy says as she rushes to Ex-Aid…

Though Gamedeus was finally destroyed at the cost of Poppy Pipopapo and Parado when they extracted the Bugster from his body, Masamune Dan survived and takes advantage of Emu no longer being able to use Hyper Muteki. The Kamen Riders are at a huge disadvantage, while Cronus doesn't hold back, and initiates Pause. All of the Kamen Riders' movements are frozen in time, and he prepares to kill them, starting with Emu…

Sento and Ryuga need to learn more about Katsuragi and his research. Setting their sights on Hokuto, they first have to get through the Sky Wall...

Now hidden in Hokuto, Sento and Ryuga try to learn more about Takumi Katsuragi from his mother, and find his hidden project data.

Sawa reveals a connection between Faust, Nanba Heavy Industries, and the Touto Government. Sento and Ryuga plan to recover Pandora's Box.

A surprise call from Nabeshima lays the foundation for Sento's plan to reclaim Pandora's Box, and a chance to capture the elusive Blood Stark...

Blood Stark's identity is revealed, and Sento races against time to finish a counter-measure against him.

Hokuto invades Touto, looking to claim Pandora's Box for themselves. As civilian casualty numbers raise, Gentoku's government instigates Kamen Rider as their military weapon.

A new contender in the Rider Wars appears before Sento and Ryuga, somehow weilding his own Sclash Driver. Hokuto's own Rider, Grease, has arrived.

Another clash between the Touto and Hokuto Riders ends with Ryuga struggling from the Sclash Driver's effects. The Hokuto Crows are given a way to power up by Blood Stark, but there's a cost...

A strange collaboration between Geiz and Tsukuyomi happens with Sougo in the year of Build, 2017. They both decide to go to Sougo's school to keep a closer eye on him. While there, they discover a growing popularity of a "game that no one can clear" with the other students. Rumors surrounding the Genius Gamer M start to surface as well, as they decide to chase the mystery by finding him. And Sougo and the others end up meeting...? Suddenly, a new Time Jacker, Ora appears!

Ora has given a father the power of Another Ex-Aid as part of a bargain for his son's life. Geiz and Sougo travel back to 2016 to help him.

Aruto tries to get a stubborn sushi chef to use a Huma Gear in his shop when Yua shows up and appears to be on Aruto's side.

Aruto and Izu sit in on a field trip to look over a Huma Gear when a young boy is teased for his father causing the Daybreak incident.

Hiden Intelligence funds a TV drama with a Huma Gear as the lead; Fuwa learns that Yaiba was the one to leak the Huma Gear footage.

Horobi takes control of Enji, affecting production on Hiden Intelligence's drama; Aruto meets with the head of ZAIA.

Aruto and Jin have their climactic battle and afterwards all seems like it's back to normal.

The president of ZAIA issues a challenge to Aruto over the acquisition of Hiden Intelligence.

Fuwa accuses Yua of fixing Horobi; Aruto learns that ZAIA's representative cheated in the contest.

Yaiba works with Jin to free Naki from Fuwa; Aruto's visit to a greenhouse is interrupted by Horobi.

Horobi protects Jin by way of his own will; Naki tells Fuwa what his real past was like.

Izu begins reliving a day where Ark keeps killing Aruto.

With Hiden Manufacturing destroyed, Aruto plans to start from the beginning again; Jin tries talking reason into MetsubouJinrai.net.

Touma is reunited with an old friend when he meets a member of the Sword of Logos who is also a father.

Ryou wonders why Touma is so obsessed with keeping promises as they try to figure out how to save Sora.

Kento is determined to find Calibur and find out what happened to his father.

Rintarou is dealing with injuries from his prior battle and Ryou is worried that Kento is going to do something stupid.

The finals of the Desire Grand Prix are underway when Keiwa Sakurai, a man down on his luck after a failed job interview, is caught in the midst of things.

Ace has won the Desire Grand Prix and the entrants for the next series assemble as they are tasked to go on a treasure hunt.

Kicking the can becomes near impossible, bringing forth a new side-quest of hatching eggs.

Ace gets another wish for winning the Desire Grand Prix, now competing with a brand new set of competitors in a new game. A game which includes the staff controlled Punk Jack from last game.

Keiwa and Neon are told that the next round is a hunt to take out Ace, but they and Tsumuri struggle with the gamemaster's decision for this illegal game.

A new gamemaster is in place and a new Desire Grand Prix is set in motion that sees the contestants living together to find a spy among them.

The Jyamato haven't been sent out in a while, so a new game begins against the Gamemaster - a game of tag.

Beroba has taken Chirami's Driver, rendering the current round of the Desire Grand Prix null.

Ace, Keiwa and Neon talk with their supporters as the Desire Grand Prix is put on hold and replaced with a special episode.

Ace and Keiwa have gone missing and Michinaga now has his wish of the power to wipe out all Kamen Rider.

Desire Royale participants have been chosen; Kekera has a plan to get Keiwa back.

"Let the game that leads to the destruction of this world, begin."

No matter what, a dangerous game that threatens peace must be stopped. Ace and the others transform into Kamen Riders to confront their troublesome "enemies"!

And the situation will come to an end in the most unprecedented way ever...

Tsumuri points her Magnum Shooter 40X at Ace... and a gunshot rings out! Was Ace shot?!

A world where everyone can be happy, just what is Ace's true wish? For that... we witness the end!