While on assignment, agent Michael Westen gets a "Burn Notice" and becomes untouchable. Having no idea what or who triggered his demise, Michael returns to his hometown, Miami, determined to find out the reason for his sudden termination.

Michael helps Madeline's friend retrieve money from a swindler, and in return he receives information about some visitors that came to his mother's home.

Michael works to rid a community in little Havana of a crime boss, all the while baiting Jason Bly at the risk of his family and friends.

Sam takes on a case for a woman named Gillian, who is being blackmailed into using her security clearance to help smuggle heroin into the United States. Meanwhile, Michael is busy trying to arrange a meeting with Philip Cowan.

Michael must rescue Sam from heroin smugglers, who happen to be ex-Special Forces, while also evading agents who are out to get him.