Dr. Samuels breaks up a late night poker game to perform emergency surgery on a gunshot victim; Morrison lets a Chinese couple perform a folk healing ritual on their dying son; and Ralph's manic stage reaches a crescendo.

A sadistic doctor orders White to get his first autopsy consent; an old friend of Dr. Craig's checks in a sex-change operation; Chandler takes over the case of the John Doe gunshot victim; and Drs. Samuels and Paxton argue over the care of a patient after renewing their intimate relationship.

Craig continues to regret his friend's sex-change operation; John Doe #12 becomes sullen and uncooperative when his real parents arrive to take him home; White's reconciliation falls through; and Armstrong delves deeply into a man's medical and family history to find out why he has persistent nose bleeds.